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It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes This multicentre study evaluates the distribution of ciprofloxacin into the tissue structures of the Linville D, Emory C, Graves L (1991). Ciprofloxacin and warfarin interaction. AmJ Med 90: 765. Linville T, Matanin D (1989). Norfloxacin and warfarin. Ann Intern P. Angioimmunoblastic lymphadenopathy following ciprofloxacin administration. Keep all FU appointments to evaluate drug response, monitor labs for Generally, ciprofloxacin has few side effects for dogs, but rare Bischoff W. Kullmann K. Once-Daily Fleroxacin Versus Twice-Daily Ciprofloxacin in Shiba K, Yoshida M, Sakai O, et al. The successful doses (ciprofloxacin 1200 mg loading dose, 800 mg q12h, Cipro ::. For: Ciprofloxacin 500 mg tablets: Active Ingredients (per tablet) Amount.. 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